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MolScribe, DECIMER HDM

Failure breakdown

Attempted: 1000 | exact: 99 (0.099)

failure mode n share of all share of failures what it points at
unparseable output 148 0.148 0.164 decoder emitted a string RDKit cannot read
stereochemistry only 27 0.027 0.030 skeleton correct; wedge/hash reading wrong
right formula, wrong bonds 1 0.001 0.001 atoms counted correctly, connectivity misread
other structural error 725 0.725 0.805 a genuinely different molecule

Accuracy by molecule size

heavy atoms n exact valid
<=10 431 0.086 0.896
<=15 325 0.123 0.849
<=20 172 0.099 0.779
<=25 70 0.071 0.771
<=30 2 0.000 1.000

Sequence length

  • Reference SMILES length, all attempted: median 20 tokens
  • Reference SMILES length, correct predictions: median 20 tokens

Longest failures

reference predicted
C=C1C(=O)O[C@H]2/C=C(\C)CC/C=C(\C)CCC(=O)[C@@H](C)CC[C@@H]12 [H][C@@]12CC[C@H](C)C(=O)CC/C(C)=C/CC/C(C)=C/[C@]1(C)OC(=O)C2=C
CSC(=S)C1=c2sc(s2)=C(C(=S)SC)SCCOCCOCCS1 [2H]P([13CH2]C)[13CH2]C(=O)[13NH2]C
O=S(=O)(O)OCN(COS(=O)(=O)O)COS(=O)(=O)O O=[S@SP2](=O)(O)OCN(CO[S@SP1](=O)(=O)O)CO[S@SP1](=O)(=O)O
C#C[C@@]1(O)CC2CCC3C(CCC4(C)C3CC[C@@H]4O)C2(C)C1 C#C[C@@]1(O)CC2CCC3C(CC[C@@]4(C)C3CCC4(C)C)C2(C)C1
O=C(OI(OC(=O)C(F)(F)F)C(F)(F)F)C(F)(F)F COC(=O)C(F)(F)F.COC(=O)C(F)(F)F.FC(F)(F)F